PDBe 3sl9

X-ray diffraction
2.2Å resolution

X-ray structure of Beta catenin in complex with Bcl9

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin beta-1 Chains: A, B, E, G
Molecule details ›
Chains: A, B, E, G
Length: 167 amino acids
Theoretical weight: 18.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P35222 (Residues: 141-305; Coverage: 21%)
Gene names: CTNNB, CTNNB1, OK/SW-cl.35, PRO2286
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
B-cell CLL/lymphoma 9 protein Chains: C, D, F, H
Molecule details ›
Chains: C, D, F, H
Length: 55 amino acids
Theoretical weight: 6.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00512 (Residues: 344-396; Coverage: 4%)
Gene name: BCL9
Sequence domains: B-cell lymphoma 9 protein

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2
Unit cell:
a: 160.89Å b: 80.7Å c: 87.94Å
α: 90° β: 102° γ: 90°
R-values:
R R work R free
0.197 0.194 0.249
Expression system: Escherichia coli BL21(DE3)