PDBe 3s9n

X-ray diffraction
3.25Å resolution

Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transferrin receptor protein 1, serum form Chains: A, B
Molecule details ›
Chains: A, B
Length: 654 amino acids
Theoretical weight: 73.53 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
UniProt:
  • Canonical: P02786 (Residues: 120-760; Coverage: 84%)
Gene name: TFRC
Sequence domains:
Structure domains:
Serotransferrin Chains: C, D
Molecule details ›
Chains: C, D
Length: 693 amino acids
Theoretical weight: 76.98 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
UniProt:
  • Canonical: P02787 (Residues: 20-698; Coverage: 100%)
Gene names: PRO1400, TF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P4322
Unit cell:
a: 234.417Å b: 234.417Å c: 169.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.254 0.254 0.289
Expression system: Cricetinae