PDBe 3s90

X-ray diffraction
1.97Å resolution

Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546)


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Talin-1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 40 amino acids
Theoretical weight: 4.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P26039 (Residues: 1512-1546; Coverage: 1%)
Gene names: Tln, Tln1
Vinculin Chains: A, B
Molecule details ›
Chains: A, B
Length: 253 amino acids
Theoretical weight: 28.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P18206 (Residues: 1-252; Coverage: 22%)
Gene name: VCL
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P1
Unit cell:
a: 48.83Å b: 61.18Å c: 71.42Å
α: 83.27° β: 79.05° γ: 69.79°
R R work R free
0.187 0.186 0.21
Expression system: Escherichia coli