PDBe 3s67

X-ray diffraction
2.26Å resolution

Crystal structure of V57P mutant of human cystatin C

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystatin-C Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 13.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01034 (Residues: 27-146; Coverage: 100%)
Gene name: CST3
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: I432
Unit cell:
a: 140.135Å b: 140.135Å c: 140.135Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.187 0.229
Expression system: Escherichia coli