PDBe 3rzy

X-ray diffraction
1.08Å resolution

Human adipocyte lipid-binding protein FABP4, Apo form at 1.08 Ang resolution.

Released:
Source organism: Homo sapiens
Primary publication:
Structural analysis of ibuprofen binding to human adipocyte fatty-acid binding protein (FABP4).
Acta Crystallogr F Struct Biol Commun 71 163-70 (2015)
PMID: 25664790

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, adipocyte Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15090 (Residues: 1-132; Coverage: 100%)
Gene name: FABP4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 32.525Å b: 53.423Å c: 74.951Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.152 0.189
Expression system: Escherichia coli