PDBe 3ryt

X-ray diffraction
3.58Å resolution

The Plexin A1 intracellular region in complex with Rac1

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plexin-A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 626 amino acids
Theoretical weight: 71.88 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P70206 (Residues: 1269-1894; Coverage: 34%)
Gene names: Kiaa4053, Plxna1
Sequence domains: Plexin cytoplasmic RasGAP domain
Structure domains:
Ras-related C3 botulinum toxin substrate 1 Chain: C
Molecule details ›
Chain: C
Length: 180 amino acids
Theoretical weight: 19.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P63000 (Residues: 1-177; Coverage: 92%)
Gene names: MIG5, RAC1, TC25
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 110.783Å b: 110.783Å c: 265.628Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.274 0.27 0.34
Expression systems:
  • Escherichia coli
  • Escherichia coli BL21(DE3)