PDBe 3rl8

X-ray diffraction
2.2Å resolution

Crystal structure of hDLG1-PDZ2 complexed with APC

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Disks large homolog 1 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 105 amino acids
Theoretical weight: 11.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12959 (Residues: 315-410; Coverage: 11%)
Gene name: DLG1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Adenomatous polyposis coli protein Chain: F
Molecule details ›
Chain: F
Length: 11 amino acids
Theoretical weight: 1.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P25054 (Residues: 2833-2843; Coverage: 0%)
Gene names: APC, DP2.5

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 67.806Å b: 52.502Å c: 87.426Å
α: 90° β: 102.42° γ: 90°
R-values:
R R work R free
0.206 0.204 0.245
Expression systems:
  • Escherichia coli
  • Not provided