PDBe 3rbq

X-ray diffraction
2Å resolution

Co-crystal structure of human UNC119 (retina gene 4) and an N-terminal Transducin-alpha mimicking peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein unc-119 homolog A Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 195 amino acids
Theoretical weight: 23.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13432 (Residues: 56-240; Coverage: 77%)
Gene names: RG4, UNC119
Sequence domains: GMP-PDE, delta subunit
Structure domains: GMP phosphodiesterase, delta subunit
Guanine nucleotide-binding protein G(t) subunit alpha-1 Chains: G, H, I, J, K, L
Molecule details ›
Chains: G, H, I, J, K, L
Length: 11 amino acids
Theoretical weight: 1.14 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P11488 (Residues: 2-11; Coverage: 3%)
Gene names: GNAT1, GNATR

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 78.546Å b: 79.713Å c: 189.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.188 0.246
Expression systems:
  • Escherichia coli
  • Not provided