PDBe 3ray

X-ray diffraction
1.73Å resolution

Crystal structure of Methyltransferase domain of human PR domain-containing protein 11

Released:
Source organism: Homo sapiens
Entry authors: Dong A, Zeng H, Loppnau P, Walker JR, Bountra C, Weigelt J, Arrowsmith CH, Edwards AM, Min J, Wu H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PR domain-containing protein 11 Chain: A
Molecule details ›
Chain: A
Length: 237 amino acids
Theoretical weight: 27.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NQV5 (Residues: 79-314; Coverage: 46%)
Gene names: PFM8, PRDM11
Structure domains: SET domain

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 31.154Å b: 55.156Å c: 106.283Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.228
Expression system: Escherichia coli BL21(DE3)