PDBe 3r6n

X-ray diffraction
2.95Å resolution

Crystal structure of a rigid four spectrin repeat fragment of the human desmoplakin plakin domain

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Desmoplakin Chains: A, B
Molecule details ›
Chains: A, B
Length: 450 amino acids
Theoretical weight: 53.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P15924 (Residues: 178-627; Coverage: 16%)
Gene name: DSP
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: C2
Unit cell:
a: 157.52Å b: 82.52Å c: 139.98Å
α: 90° β: 125.54° γ: 90°
R-values:
R R work R free
0.221 0.216 0.265
Expression system: Escherichia coli BL21