PDBe 3qqd

X-ray diffraction
1.65Å resolution

Human SOD1 H80R variant, P212121 crystal form

Released:

Function and Biology Details

Reaction catalysed:
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Superoxide dismutase [Cu-Zn] Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 15.92 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain
Superoxide dismutase [Cu-Zn] Chain: B
Molecule details ›
Chain: B
Length: 154 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

2 bound ligands:

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P212121
Unit cell:
a: 40.245Å b: 58.427Å c: 104.825Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.147 0.144 0.183
Expression system: Saccharomyces cerevisiae