PDBe 3qnt

X-ray diffraction
2.83Å resolution

NPC1L1 (NTD) Structure

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NPC1-like intracellular cholesterol transporter 1 Chain: A
Molecule details ›
Chain: A
Length: 265 amino acids
Theoretical weight: 28.07 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9UHC9 (Residues: 22-284; Coverage: 20%)
Gene name: NPC1L1
Sequence domains: Niemann-Pick C1 N terminus

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 73.235Å b: 107.133Å c: 68.718Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.226 0.29
Expression system: Trichoplusia ni