PDBe 3q74

X-ray diffraction
1.79Å resolution

Crystal Structure Analysis of the L7A Mutant of the Apo Form of Human Alpha Class Glutathione Transferase

Released:
Source organism: Homo sapiens
Entry authors: Fanucchi S, Achilonu IA, Khoza TN, Fernandes MA, Gildenhuys S, Dirr HW

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 221 amino acids
Theoretical weight: 25.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08263 (Residues: 2-222; Coverage: 100%)
Gene name: GSTA1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: C2
Unit cell:
a: 99.345Å b: 91.317Å c: 51.374Å
α: 90° β: 93.01° γ: 90°
R-values:
R R work R free
0.206 0.203 0.27
Expression system: Escherichia coli