PDBe 3q18

X-ray diffraction
1.7Å resolution

Human Glutathione Transferase O2

Released:

Function and Biology Details

Reactions catalysed:
2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate
RX + glutathione = HX + R-S-glutathione
Methylarsonate + 2 glutathione = methylarsonite + glutathione disulfide + H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase omega-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 239 amino acids
Theoretical weight: 27.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H4Y5 (Residues: 1-239; Coverage: 98%)
Gene name: GSTO2
Sequence domains:
Structure domains: Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P21
Unit cell:
a: 46.659Å b: 85.718Å c: 60.359Å
α: 90° β: 95.26° γ: 90°
R-values:
R R work R free
0.159 0.157 0.186
Expression system: Escherichia coli