PDBe 3pl7

X-ray diffraction
2.61Å resolution

Crystal structure of Bcl-xL in complex with the BaxBH3 domain

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bcl-2-like protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 181 amino acids
Theoretical weight: 20.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07817 (Residues: 1-209; Coverage: 73%)
Gene names: BCL2L, BCL2L1, BCLX
Sequence domains:
Apoptosis regulator BAX Chain: C
Molecule details ›
Chain: C
Length: 34 amino acids
Theoretical weight: 3.84 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q07812 (Residues: 48-81; Coverage: 18%)
Gene names: BAX, BCL2L4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: C2221
Unit cell:
a: 70.246Å b: 99.05Å c: 113.143Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.186 0.25
Expression systems:
  • Escherichia coli
  • Not provided