› 3p86

X-ray diffraction
2.5Å resolution

Crystal structure of CTR1 kinase domain mutant D676N in complex with staurosporine

Released:
DOI: 10.2210/pdb3p86/pdb
PDB entry 3p86 coloured by chain, front view.
PDB entry 3p86 coloured by chain, side view.
PDB entry 3p86 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Protein kinase domain of CTR1 from Arabidopsis thaliana promotes ethylene receptor cross talk.
Mayerhofer H, Panneerselvam S, Mueller-Dieckmann J
J Mol Biol 415 768-79 (2012)
PMID: 22155294

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170232 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase CTR1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 309 amino acids
Theoretical weight: 35.22 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05609 (Residues: 540-821; Coverage: 34%)
Gene names: At5g03730, CTR1, F17C15_150
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand STU 1 x STU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P42212
Unit cell:
a: 122.334Å b: 122.334Å c: 95.011Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.232
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Ethylene signaling: simple ligand, complex regulation.
Merchante et al. (2013)
6 more

2 mentions without citation

ProtCID: a data resource for structural information on protein interactions.
Xu et al. (2020)
1 more