PDBe 3p1m

X-ray diffraction
2.54Å resolution

Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster

Released:
Source organism: Homo sapiens
Entry authors: Chaikuad A, Johansson C, Krojer T, Yue WW, Phillips C, Bray JE, Pike ACW, Muniz JRC, Vollmar M, Weigelt J, Arrowsmith CH, Edwards AM, Bountra C, Kavanagh K, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adrenodoxin, mitochondrial Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 132 amino acids
Theoretical weight: 14.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10109 (Residues: 61-184; Coverage: 67%)
Gene names: ADX, FDX1
Sequence domains: 2Fe-2S iron-sulfur cluster binding domain
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P32
Unit cell:
a: 76.576Å b: 76.576Å c: 234.41Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.204 0.241
Expression system: Escherichia coli