› 3oz6

X-ray diffraction
2.37Å resolution

Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960

Released:
DOI: 10.2210/pdb3oz6/pdb
PDB entry 3oz6 coloured by chain, front view.
PDB entry 3oz6 coloured by chain, side view.
PDB entry 3oz6 coloured by chain, top view.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Wernimont AK, Lew J, Lin YH, Sullivan H, Hassanali A, Kozieradzki I, Cossar D, Arrowsmith CH, Bochkarev A, Bountra C, Edwards AM, Weigelt J, Hui R, Neculai AM, Hutchinson A, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107144 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 388 amino acids
Theoretical weight: 44.82 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A3FQ79 (Residues: 4-390; Coverage: 55%)
Gene name: cgd2_1960
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 74.298Å b: 91.746Å c: 119.985Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.231 0.26
Expression system: Escherichia coli BL21

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