PDBe 3ox8

X-ray diffraction
2.16Å resolution

Crystal Structure of HLA A*02:03 Bound to HBV Core 18-27

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
MHC class I antigen Chains: A, D
Molecule details ›
Chains: A, D
Length: 275 amino acids
Theoretical weight: 31.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains:
Beta-2-microglobulin Chains: B, E
Molecule details ›
Chains: B, E
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
External core antigen Chains: C, F
Molecule details ›
Chains: C, F
Length: 10 amino acids
Theoretical weight: 1.16 KDa
Source organism: Hepatitis B virus
Expression system: Not provided
UniProt:
  • Canonical: P0C6H2 (Residues: 47-56; Coverage: 5%)
Gene name: C

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P1
Unit cell:
a: 60.279Å b: 68.269Å c: 68.318Å
α: 70.2° β: 84.4° γ: 84.45°
R-values:
R R work R free
0.185 0.182 0.234
Expression systems:
  • Escherichia coli
  • Not provided