PDBe 3ods

X-ray diffraction
1.9Å resolution

Crystal structure of the K185A mutant of the N-terminal domain of human Symplekin

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Symplekin Chain: A
Molecule details ›
Chain: A
Length: 415 amino acids
Theoretical weight: 46.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92797 (Residues: 1-395; Coverage: 31%)
Gene names: SPK, SYMPK
Sequence domains: Domain of unknown function (DUF3453)
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P1
Unit cell:
a: 32.193Å b: 44.039Å c: 63.463Å
α: 79.45° β: 80.55° γ: 73.84°
R-values:
R R work R free
0.179 0.176 0.231
Expression system: Escherichia coli