PDBe 3nux

X-ray diffraction
2.7Å resolution

CDK6 (monomeric) in complex with inhibitor

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclin-dependent kinase 6 Chain: A
Molecule details ›
Chain: A
Length: 307 amino acids
Theoretical weight: 35.02 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q00534 (Residues: 1-301; Coverage: 92%)
Gene names: CDK6, CDKN6
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: I4
Unit cell:
a: 101.96Å b: 101.96Å c: 59.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.243 0.266
Expression system: Spodoptera frugiperda