PDBe 3nnx

X-ray diffraction
2.28Å resolution

Crystal structure of phosphorylated P38 alpha in complex with DP802

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 14 Chain: A
Molecule details ›
Chain: A
Length: 354 amino acids
Theoretical weight: 40.69 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q16539 (Residues: 1-354; Coverage: 98%)
Gene names: CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2, SAPK2A
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: C2
Unit cell:
a: 87.825Å b: 62.723Å c: 90.13Å
α: 90° β: 110.74° γ: 90°
R-values:
R R work R free
0.222 0.218 0.285
Expression system: Spodoptera frugiperda