PDBe 3nmw

X-ray diffraction
1.6Å resolution

Crystal structure of armadillo repeats domain of APC

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenomatous polyposis coli protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 354 amino acids
Theoretical weight: 40.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P25054 (Residues: 407-751; Coverage: 12%)
Gene names: APC, DP2.5
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P1
Unit cell:
a: 51.389Å b: 52.682Å c: 63.451Å
α: 90.31° β: 89.95° γ: 95.16°
R-values:
R R work R free
0.17 0.168 0.201
Expression system: Escherichia coli