PDBe 3mvt

X-ray diffraction
2.2Å resolution

Crystal structure of apo mADA at 2.2A resolution

Released:
Source organism: Mus musculus

Function and Biology Details

Reaction catalysed:
Adenosine + H(2)O = inosine + NH(3)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine deaminase Chains: A, C
Molecule details ›
Chains: A, C
Length: 349 amino acids
Theoretical weight: 39.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03958 (Residues: 4-352; Coverage: 99%)
Gene name: Ada
Sequence domains: Adenosine/AMP deaminase
Structure domains: Metal-dependent hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 98.833Å b: 93.827Å c: 86.18Å
α: 90° β: 96.76° γ: 90°
R-values:
R R work R free
0.19 0.187 0.245
Expression system: Escherichia coli