PDBe 3m9k

X-ray diffraction
1.5Å resolution

Crystal structure of human thioredoxin C69/73S double-mutant, oxidized form

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin Chains: A, B
Molecule details ›
Chains: A, B
Length: 105 amino acids
Theoretical weight: 11.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P6
Unit cell:
a: 125.62Å b: 125.62Å c: 33.55Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.185 0.184 0.211
Expression system: Escherichia coli BL21(DE3)