PDBe 3ln4

X-ray diffraction
1.3Å resolution

Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, B-41 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 31.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30479 (Residues: 25-298; Coverage: 81%)
Gene names: HLA-B, HLAB
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Heterogeneous nuclear ribonucleoproteins C1/C2 Chain: C
Molecule details ›
Chain: C
Length: 16 amino acids
Theoretical weight: 1.7 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P07910 (Residues: 102-117; Coverage: 5%)
Gene names: HNRNPC, HNRPC

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 50.777Å b: 81.992Å c: 109.81Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.155 0.155 0.177
Expression systems:
  • Escherichia coli
  • Not provided