› 3lij

X-ray diffraction
1.9Å resolution

Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP

Released:
DOI: 10.2210/pdb3lij/pdb
PDB entry 3lij coloured by chain, front view.
PDB entry 3lij coloured by chain, side view.
PDB entry 3lij coloured by chain, top view.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Qiu W, Hutchinson A, Wernimont A, Walker JR, Sullivan H, Lin Y-H, Mackenzie F, Kozieradzki I, Cossar D, Schapira M, Senisterra G, Vedadi M, Arrowsmith CH, Bountra C, Weigelt J, Edwards AM, Bochkarev A, Hui R, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176925 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Chain: A
Molecule details ›
Chain: A
Length: 494 amino acids
Theoretical weight: 56.58 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5CS01 (Residues: 42-517; Coverage: 91%)
Gene name: cgd5_820
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand CA 4 x CA
Ligand MG 1 x MG
Ligand ANP 1 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P21
Unit cell:
a: 57.08Å b: 88.06Å c: 58.61Å
α: 90° β: 118.07° γ: 90°
R-values:
R R work R free
0.203 0.203 0.229
Expression system: Escherichia coli

Quick links