PDBe 3l9q

X-ray diffraction
1.7Å resolution

Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain


Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
DNA primase large subunit Chains: A, B
Molecule details ›
Chains: A, B
Length: 195 amino acids
Theoretical weight: 22.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P49643 (Residues: 272-464; Coverage: 38%)
Gene names: PRIM2, PRIM2A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: C2
Unit cell:
a: 109.441Å b: 53.05Å c: 88.844Å
α: 90° β: 115.09° γ: 90°
R R work R free
0.132 0.13 0.169
Expression system: Escherichia coli