PDBe 3l6x

X-ray diffraction
2.4Å resolution

Crystal structure of p120 catenin in complex with E-cadherin

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin delta-1 Chain: A
Molecule details ›
Chain: A
Length: 584 amino acids
Theoretical weight: 65.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60716 (Residues: 324-937; Coverage: 60%)
  • Best match: O60716-21 (Residues: 223-832)
Gene names: CTNND1, KIAA0384
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
E-Cad/CTF3 Chain: B
Molecule details ›
Chain: B
Length: 18 amino acids
Theoretical weight: 2.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P12830 (Residues: 756-773; Coverage: 2%)
Gene names: CDH1, CDHE, UVO

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P3121
Unit cell:
a: 92.403Å b: 92.403Å c: 171.89Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.201 0.234
Expression systems:
  • Escherichia coli
  • Not provided