PDBe 3l2b

X-ray diffraction
2.27Å resolution

Crystal structure of the CBS and DRTGG domains of the regulatory region of Clostridium perfringens pyrophosphatase complexed with activator, diadenosine tetraphosphate


Function and Biology Details

Reaction catalysed:
Diphosphate + H(2)O = 2 phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Cobalt-dependent inorganic pyrophosphatase Chains: A, B
Molecule details ›
Chains: A, B
Length: 245 amino acids
Theoretical weight: 26.97 KDa
Source organism: Clostridium perfringens str. 13
Expression system: Escherichia coli
  • Canonical: Q8XIQ9 (Residues: 66-306; Coverage: 44%)
Gene name: CPE2055
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 63.847Å b: 71.764Å c: 116.334Å
α: 90° β: 90° γ: 90°
R R work R free
0.211 0.209 0.259
Expression system: Escherichia coli