PDBe 3l15

X-ray diffraction
2Å resolution

Human Tead2 transcriptional factor

Released:
Source organism: Homo sapiens
Primary publication:
Structural and functional analysis of the YAP-binding domain of human TEAD2.
Proc. Natl. Acad. Sci. U.S.A. 107 7293-8 (2010)
PMID: 20368466

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional enhancer factor TEF-4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 231 amino acids
Theoretical weight: 26.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15562 (Residues: 217-447; Coverage: 52%)
Gene names: TEAD2, TEF4
Sequence domains: YAP binding domain
Structure domains: Coagulation Factor XIII; Chain A, domain 1

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: C2
Unit cell:
a: 121.144Å b: 61.567Å c: 80.472Å
α: 90° β: 117.27° γ: 90°
R-values:
R R work R free
0.192 0.188 0.244
Expression system: Escherichia coli