PDBe 3kxu

X-ray diffraction
1.85Å resolution

Crystal structure of human ferritin FTL498InsTC pathogenic mutant


Function and Biology Details

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Ferritin light chain Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P02792 (Residues: 1-172; Coverage: 98%)
Gene name: FTL
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: I432
Unit cell:
a: 151.355Å b: 151.355Å c: 151.355Å
α: 90° β: 90° γ: 90°
R R work R free
0.18 0.179 0.211
Expression system: Escherichia coli