PDBe 3knb

X-ray diffraction
1.4Å resolution

Crystal structure of the titin C-terminus in complex with obscurin-like 1

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Titin Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 10.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8WZ42 (Residues: 34253-34350; Coverage: 0%)
Gene name: TTN
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins
Obscurin-like protein 1 Chain: B
Molecule details ›
Chain: B
Length: 107 amino acids
Theoretical weight: 10.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O75147 (Residues: 1-105; Coverage: 6%)
Gene names: KIAA0657, OBSL1
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: P31
Unit cell:
a: 60.91Å b: 60.91Å c: 42.05Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.165 0.164 0.195
Expression system: Escherichia coli BL21