PDBe 3km8

X-ray diffraction
2Å resolution

Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine

Released:
Source organism: Mus musculus
Entry authors: Fan X, Gao Y

Function and Biology Details

Reaction catalysed:
Adenosine + H(2)O = inosine + NH(3)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine deaminase Chains: A, B
Molecule details ›
Chains: A, B
Length: 352 amino acids
Theoretical weight: 40.01 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03958 (Residues: 1-352; Coverage: 100%)
Gene name: Ada
Sequence domains: Adenosine/AMP deaminase
Structure domains: Metal-dependent hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-002+
Spacegroup: C2
Unit cell:
a: 100.337Å b: 93.616Å c: 85.416Å
α: 90° β: 97.35° γ: 90°
R-values:
R R work R free
0.203 0.202 0.223
Expression system: Escherichia coli