PDBe 3kd0

X-ray diffraction
1.7Å resolution

Human thioredoxin C35S,C62S,C69S,C73S mutant showing cadmium chloride bound to the active site

Source organism: Homo sapiens
Entry authors: Hall G, Emsley J

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Thioredoxin Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P6122
Unit cell:
a: 53.635Å b: 53.635Å c: 154.148Å
α: 90° β: 90° γ: 120°
R R work R free
0.247 0.232 0.279
Expression system: Escherichia coli