PDBe 3k71

X-ray diffraction
3.95Å resolution

Structure of integrin alphaX beta2 ectodomain

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero octamer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin alpha-X Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 1095 amino acids
Theoretical weight: 120.71 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P20702 (Residues: 20-1103; Coverage: 95%)
Gene names: CD11C, ITGAX
Sequence domains:
Structure domains:
Integrin beta-2 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 687 amino acids
Theoretical weight: 75.94 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P05107 (Residues: 23-699; Coverage: 91%)
Gene names: CD18, ITGB2, MFI7
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 149.664Å b: 165.745Å c: 537.676Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.35 0.35 0.373
Expression system: Cricetulus griseus