PDBe 3k05

X-ray diffraction
1.33Å resolution

The crystal structure of MDC1 BRCT T2067D in complex with a minimal recognition tetrapeptide with an amidated C-terminus

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
phospho peptide Chains: C, D
Molecule details ›
Chains: C, D
Length: 5 amino acids
Theoretical weight: 603 Da
Source organism: Homo sapiens
Expression system: Not provided
Mediator of DNA damage checkpoint protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 200 amino acids
Theoretical weight: 21.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14676 (Residues: 1891-2089; Coverage: 10%)
Gene names: KIAA0170, MDC1, NFBD1
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 55.642Å b: 74.58Å c: 103.408Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.182 0.202
Expression systems:
  • Not provided
  • Escherichia coli