PDBe 3jcc

Electron Microscopy

Structure of Simian Immunodeficiency Virus Envelope Spikes bound with CD4 and Monoclonal Antibody 36D5

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Envelope glycoprotein gp120 Chains: A, E, I
Molecule details ›
Chains: A, E, I
Length: 448 amino acids
Theoretical weight: 50.13 KDa
Source organism: Simian immunodeficiency virus
Antibody 36D5 light chain Chain: B
Molecule details ›
Chain: B
Length: 207 amino acids
Theoretical weight: 22.29 KDa
Source organism: Homo sapiens
Antibody 36D5 heavy chain Chain: C
Molecule details ›
Chain: C
Length: 232 amino acids
Theoretical weight: 25.12 KDa
Source organism: Homo sapiens
T-cell surface glycoprotein CD4 Chain: D
Molecule details ›
Chain: D
Length: 175 amino acids
Theoretical weight: 19.44 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: NEW P01730 (Residues: 26-200; Coverage: 40%)
Gene name: CD4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Relevant EMDB volumes: EMD-6543