› 3is5

X-ray diffraction
2.55Å resolution

Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720

Released:
DOI: 10.2210/pdb3is5/pdb
PDB entry 3is5 coloured by chain, front view.
PDB entry 3is5 coloured by chain, side view.
PDB entry 3is5 coloured by chain, top view.
Source organism: Toxoplasma gondii ME49
Entry authors: Wernimont AK, Artz JD, Senisterra G, MacKenzie F, Hutchinson A, Kozieradzki I, Cossar D, Bochkarev A, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Hui R, Lin YH, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163665 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-dependent protein kinase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 285 amino acids
Theoretical weight: 32.61 KDa
Source organism: Toxoplasma gondii ME49
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand ANP 6 x ANP
Ligand CA 3 x CA
Ligand GOL 7 x GOL
Ligand MG 6 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P32
Unit cell:
a: 113.973Å b: 113.973Å c: 153.471Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.218 0.259
Expression system: Escherichia coli

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