PDBe 3ifl

X-ray diffraction
1.5Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Amyloid-beta protein 40 Chain: P
Molecule details ›
Chain: P
Length: 7 amino acids
Theoretical weight: 891 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 672-678; Coverage: 1%)
Gene names: A4, AD1, APP
12A11 FAB antibody heavy chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.98 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
Structure domains: Immunoglobulins
12A11 FAB antibody light chain Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.09 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 42.97Å b: 85.98Å c: 57.45Å
α: 90° β: 94.67° γ: 90°
R-values:
R R work R free
0.18 0.178 0.206
Expression systems:
  • Not provided
  • Cricetulus griseus