PDBe 3i9p

X-ray diffraction
1.9Å resolution

Crystal structure of human transthyretin - wild type

Released:
Source organism: Homo sapiens
Entry authors: Lima LMTR, Foguel D

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 116 amino acids
Theoretical weight: 12.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 30-145; Coverage: 91%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P21212
Unit cell:
a: 42.42Å b: 83.49Å c: 63.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.255
Expression system: Escherichia coli