PDBe 3i6l

X-ray diffraction
2.4Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A-24 alpha chain Chain: D
Molecule details ›
Chain: D
Length: 274 amino acids
Theoretical weight: 31.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05534 (Residues: 25-298; Coverage: 80%)
Gene names: HLA-A, HLAA
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: E
Molecule details ›
Chain: E
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Nucleoprotein Chain: F
Molecule details ›
Chain: F
Length: 9 amino acids
Theoretical weight: 1.09 KDa
Source organism: SARS coronavirus
Expression system: Not provided
UniProt:
  • Canonical: P59595 (Residues: 346-354; Coverage: 2%)
Gene names: 9a, N

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 70.422Å b: 85.823Å c: 92.221Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.213 0.284
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided