PDBe 3i01

X-ray diffraction
2.15Å resolution

Native structure of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase from Moorella thermoacetica, water-bound C-cluster.

Released:

Function and Biology Details

Reactions catalysed:
CO + H(2)O + 2 oxidized ferredoxin = CO(2) + 2 reduced ferredoxin + 2 H(+)
Acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein]
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit beta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 674 amino acids
Theoretical weight: 73.01 KDa
Source organism: Moorella thermoacetica
UniProt:
  • Canonical: P27989 (Residues: 1-674; Coverage: 100%)
Sequence domains: Prismane/CO dehydrogenase family
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P1
Unit cell:
a: 99.651Å b: 136.87Å c: 140.864Å
α: 101.26° β: 109.11° γ: 104.08°
R-values:
R R work R free
0.189 0.186 0.242