PDBe 3hb1

X-ray diffraction
2.51Å resolution

Crystal structure of ed-eya2 complexed with Alf3


Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Eyes absent homolog 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 274 amino acids
Theoretical weight: 31.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O00167 (Residues: 269-538; Coverage: 50%)
Gene names: EAB1, EYA2
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: I4
Unit cell:
a: 183.941Å b: 183.941Å c: 119.976Å
α: 90° β: 90° γ: 90°
R R work R free
0.205 0.2 0.24
Expression system: Escherichia coli