PDBe 3h2v

X-ray diffraction
2.9Å resolution

Human raver1 RRM1 domain in complex with human vinculin tail domain Vt

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonucleoprotein PTB-binding 1 Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 74 amino acids
Theoretical weight: 8.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IY67 (Residues: 59-130; Coverage: 12%)
Gene names: KIAA1978, RAVER1
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits
Vinculin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 188 amino acids
Theoretical weight: 21.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P18206 (Residues: 944-1134; Coverage: 17%)
  • Best match: P18206-2 (Residues: 879-1066)
Gene name: VCL
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P1
Unit cell:
a: 41.818Å b: 70.921Å c: 99.342Å
α: 89.77° β: 90.04° γ: 104.04°
R-values:
R R work R free
0.213 0.21 0.277
Expression system: Escherichia coli