PDBe 3gki

X-ray diffraction
1.8Å resolution

NPC1(NTD):cholesterol

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NPC intracellular cholesterol transporter 1 Chain: A
Molecule details ›
Chain: A
Length: 232 amino acids
Theoretical weight: 25.74 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: O15118 (Residues: 23-252; Coverage: 18%)
Gene name: NPC1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P64
Unit cell:
a: 65.691Å b: 65.691Å c: 82.367Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.174 0.207
Expression system: Trichoplusia ni