PDBe 3frs

X-ray diffraction
2.61Å resolution

Structure of human IST1(NTD) (residues 1-189)(p43212)

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
IST1 homolog Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 21.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53990 (Residues: 5-189; Coverage: 51%)
  • Best match: P53990-6 (Residues: 1-41)
Gene names: IST1, KIAA0174
Sequence domains: Regulator of Vps4 activity in the MVB pathway
Structure domains: Ferritin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF, SSRL BEAMLINE BL11-1
Spacegroup: P43212
Unit cell:
a: 57.18Å b: 57.18Å c: 157.262Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.261 0.259 0.298
Expression system: Escherichia coli