PDBe 3ff8

X-ray diffraction
2Å resolution

Structure of NK cell receptor KLRG1 bound to E-cadherin

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cadherin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P12830 (Residues: 155-254; Coverage: 12%)
Gene names: CDH1, CDHE, UVO
Sequence domains: Cadherin domain
Structure domains: Cadherins
Killer cell lectin-like receptor subfamily G member 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 114 amino acids
Theoretical weight: 13.15 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW O88713 (Residues: 75-188; Coverage: 61%)
Gene names: Klrg1, Mafa
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 53.776Å b: 90.526Å c: 107.593Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.212 0.253
Expression system: Escherichia coli