PDBe 3ery

X-ray diffraction
1.95Å resolution

Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors

Released:

Function and Biology Details

Reaction catalysed:
2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO(2)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
H-2 class I histocompatibility antigen, L-D alpha chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 174 amino acids
Theoretical weight: 20.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01897 (Residues: 25-198; Coverage: 52%)
Gene name: H2-L
Structure domains: MHC class I-like antigen recognition-like
2-oxoglutarate dehydrogenase, mitochondrial Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 9 amino acids
Theoretical weight: 1.06 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q02218 (Residues: 932-940; Coverage: 1%)
Gene name: OGDH

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21
Unit cell:
a: 47.163Å b: 74.323Å c: 53.255Å
α: 90° β: 107.65° γ: 90°
R-values:
R R work R free
0.232 0.232 0.283
Expression systems:
  • Escherichia coli
  • Not provided