PDBe 3e1u

X-ray diffraction
2.3Å resolution

The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA dC->dU-editing enzyme APOBEC-3G Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 22.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HC16 (Residues: 197-380; Coverage: 48%)
Gene names: APOBEC3G, MDS019
Sequence domains: APOBEC-like C-terminal domain
Structure domains: Cytidine Deaminase, domain 2

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 83.464Å b: 57.329Å c: 40.578Å
α: 90° β: 96.46° γ: 90°
R-values:
R R work R free
0.252 0.251 0.267
Expression system: Escherichia coli